Medical

An alternative cover edition for this ISBN can be found here and here.The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer - from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

In his most extraordinary book, Oliver Sacks recounts the stories of patients lost in the bizarre, apparently inescapable world of neurological disorders. These are case studies of people who have lost their memories and with them the greater part of their pasts; who are no longer able to recognize people or common objects; whose limbs have become alien; who are afflicted and yet are gifted with uncanny artistic or mathematical talents. In Dr Sacks' splendid and sympathetic telling, each tale is a unique and deeply human study of life struggling against incredible adversity.

Upon its original publication, Plagues and Peoples was an immediate critical and popular success, offering a radically new interpretation of world history as seen through the extraordinary impact--political, demographic, ecological, and psychological--of disease on cultures. From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, the history of disease is the history of humankind. With the identification of AIDS in the early 1980s, another chapter has been added to this chronicle of events, which William McNeill explores in his new introduction to this updated editon.Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. "A brilliantly conceptualized and challenging achievement" (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

Can we live robustly until our last breath?Do we have to suffer from debilitating conditions and sickness? Is it possible to add more vibrant years to our lives? In the #1 New York Times bestselling The End of Illness , Dr. David Agus tackles these fundamental questions and dismantles misperceptions about what “health” really means. Presenting an eye-opening picture of the human body and all the ways it works—and fails—Dr. Agus shows us how a new perspective on our individual health will allow us to achieve a long, vigorous life.Offering insights and access to powerful new technologies that promise to transform medicine, Dr. Agus emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that. A bold call for all of us to become our own personal health advocates, The End of Illness is a moving departure from orthodox thinking.

Upon becoming a new mother, Eula Biss addresses a chronic condition of fear--fear of the government, the medical establishment, and what is in your child's air, food, mattress, medicine, and vaccines. She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

In her new book, Arianna Huffington, the co-founder and editor-in-chief of The Huffington Post, and the author of the #1 New York Times bestseller Thrive delves into the sleep revolution that is happening all across the world – a revolution that can transform our lives. Sleep, she writes, is one of humanity’s great unifiers, binding us to each other, to our ancestors, to our past, and to the future. Yet we find ourselves in the middle of a crisis of sleep deprivation, with devastating effects on our health, our happiness, our job performance, and our relationships. Only by renewing our relationship with sleep, she writes, can we take control of our lives, live more fully, be more engaged with ourselves and with the world, and more able to meet the inevitable challenges we all face. In Thrive, Arianna Huffington introduced her readers to the importance of sleep as a part of redefining success through well-being, wisdom, wonder, and giving. The topic struck such a powerful chord, resonating so intensely with her readers and her audiences around the world that she realized the power of sleep needed a full exploration. The result is a sweeping, scientifically rigorous, and deeply personal look at sleep, from its history though the ages and the current crisis of sleep deprivation, to the mysteries of dreams and the golden age of sleep science that is revealing all the ways sleep plays a vital role in our health, happiness, well-being, and productivity. In The Sleep Revolution, Arianna identifies the many ways our cultural dismissal of sleep as time wasted undermines our health and our decision-making, and ravages our relationships, our work lives, and even our sex lives. She takes on sleep from every angle, exploring the latest science on sleep, the manipulative and dangerous sleeping pill industry, and all the ways our addiction to technology disrupts our sleep. She also presents scientific recommendations and expert tips on how we can all achieve better and more restorative sleep, and learn how to make the power of sleep work for us. Most important, by highlighting the many areas where sleep’s benefits are being rediscovered – from the world of sports and technology to college campuses, the hotel industry, and even workplaces around the world – she points the way forward to amazing innovations, reforms, and inventions rooted in our new love affair with sleep. In today’s 24/7 fast-paced, always-connected, perpetually harried, and sleep-deprived world, the hunger for sleep is only getting stronger. The Sleep Revolution both sounds the alarm on the worldwide sleep crisis, and offers a road map for how we can take back our sleep and transform our lives and our world.

A Science Friday pick for book of the year, 2019One of America's top doctors reveals how AI will empower physicians and revolutionize patient care Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard.Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved.

A magnificently reported and soulfully crafted exploration of the human immune system–the key to health and wellness, life and death. An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

Molecular Biology of the Cell is the classic in-dept text reference in cell biology. By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

A world-famous ethnobotanist scours the planet in search of new natural cures, unveiling the healing power in snake venom, leech saliva, rain-forest frogs, and other natural sources. Reprint.

In 1918 the Great Flu Epidemic killed an estimated 40 million people virtually overnight. If such a plague returned today, taking a comparable percentage of the U.S. population with it, 1.5 million Americans would die.The fascinating, true story of the world's deadliest disease.In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out.Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for "The New York Times," unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.

This is the book that has given thousands of sufferers new hope--a gentle, effective way to find real relief from back pain, without painkillers, without surgery, without spending days on end in bed. Dr. John Sarno 's revolutionary approach to back pain is based on his discovery that tension is the underlying cause of most back problems--leading to an often unrecognized condition called Tension Mytosis Syndrome. In this book--the first to explain the psychophysiology, manifestations, and treatment of TMS--you'll find clear steps, sensible advice, and simple illustrations to help you find relief, prevent future pain...and live life fully once again.

From the best-selling author of SPONTANEOUS HEALING, a brilliantly conceived, safe and effective eight-week programme for improving and maintaining health. Dr Weil first explains, then shows how, week by week, gradual changes can lead to long-term benefits such as greater vitality, weight loss and a body which heals itself. Incorporating alternative medicines and treatments, he provides specific and detailed information on diet (with 50 recipes), exercise, stress reduction techniques, and vitamins and supplements. He also customizes programmes for a dozen categories, such as pregnant women, people at risk of cancer, overweight people, and senior citizens. Building on the breakthrough thinking of SPONTANEOUS HEALING, Dr Weil provides an invaluable means to maintain health and lessen the need for medical intervention.

Have you ever seen something that wasn’t really there? Heard someone call your name in an empty house? Sensed someone following you and turned around to find nothing? Hallucinations don’t belong wholly to the insane. Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.

Just before dawn on a Sunday morning, three teenage boys go surfing. While driving home exhausted, the boys are involved in a fatal car accident on a deserted road. Two of the boys are wearing seat belts; one goes through the windshield. The doctors declare him brain-dead shortly after arriving at the hospital, but his heart is still beating.The Heart takes place over the twenty-four hours surrounding the resulting heart transplant, as life is taken from a young man and given to a woman close to death. In gorgeous, ruminative prose, it examines the deepest feelings of everyone involved as they navigate decisions of life and death.As stylistically audacious as it is emotionally explosive, The Heart mesmerized readers in France, where it has been hailed as the breakthrough work of a new literary star. With the precision of a surgeon and the language of a poet, de Kerangal has made a major contribution to both medicine and literature with an epic tale of grief, hope, and survival.

Ai rồi cũng chết! là một tuyệt phẩm đánh động lòng người được viết nên bởi bác sĩ kiêm tác giả best-seller Atul Gawande. Cuốn sách không chỉ có khả năng lay chuyển ngành y học hiện đại, mà nó còn sẽ giúp làm biến đổi hoàn toàn cuộc sống của muôn người - bao gồm chính bạn!Ngành y học thế giới đã có nhiều bước phát triển vượt bậc trong những năm giảm thiểu tỉ lệ tử vong trẻ sơ sinh, nâng cao tỉ lệ sống sót sau chấn thương, chữa trị và kiểm soát được nhiều loại bệnh tật - kể cả nhiều căn bệnh từng được xem là không có thuốc chữa trong quá khứ. Nhưng dù có bành trướng hùng mạnh đến đâu, y học vẫn muôn đời bất lực trước quy luật sinh-lão-bệnh-tử bất biến của con ngườ Mỗi khi con người phải đối diện với Tuổi Già và Cái Chết, những công cụ y học vốn dĩ quyền năng bỗng chốc phản bội lại chính lý tưởng cứu nhân độ thế mà chúng đang phục vụ.Bằng những công trình nghiên cứu khoa học giá trị và những câu chuyện sống động từ các bệnh nhân và người thân của chính mình, bác sĩ Gawande bóc trần cho chúng ta thấy những hệ lụy và nỗi đau mà con người phải gánh chịu bởi nghịch lý trên. Viện dưỡng lão vốn dĩ được lập ra với mục đích ban đầu tốt đẹp là giúp cho người cao tuổi có một cuộc sống hạnh phúc và viên mãn bất chấp tuổi già, nhưng nhiều nhà dưỡng lão ngày nay bị biến tướng thành những tòa nhà khép kín không khác gì nhà tù, nơi mà người già không được phép ăn những món ăn họ thích và không được phép làm những gì mình muốn. Nhiều bác sĩ được đào tạo xuất sắc về mặt chuyên môn, nhưng lại không biết cách làm thế nào để nói cho bệnh nhân biết sự thật về bệnh tình của họ; thay vào đó, bác sĩ lại vin vào những hy vọng hão huyền về khả năng cứu sống người bệnh của y học và đề xuất cho bệnh nhân hàng loạt biện pháp chữa trị để nuôi những hy vọng hão đó. Rốt cuộc, hành động này chỉ khiến cho người bệnh và cả thân nhân của họ thêm hao mòn khổ sở chứ không hề mang lại ích lợi gì cho họ cả về mặt thể xác lẫn tinh thần.Trong những cuốn sách của mình, bác sĩ phẫu thuật Atul Gawande đã dùng ngòi bút mạnh mẽ không chút sợ hãi của mình tiết lộ cho chúng ta biết sự thật đằng sau ngành y cũng như những cuộc chiến mà các thầy thuốc như ông phải đối mặt và tranh đấu vượt qua. Lần này, với tác phẩm Ai rồi cũng chết!, ông phơi bày cho chúng ta thấy những giới hạn và nhược điểm của ngành y - trong cả chuyên môn của ông lẫn những chuyên ngành khác - khi cuộc sống con người bị đe dọa bởi sự lão hóa và cái chết. Qua đó, ông cũng đồng thời khám phá ra rằng mọi chuyện đều có cách giải quyết, rằng chúng ta hoàn toàn có thể làm khác đi, để mang lại cuộc sống tốt đẹp hơn cho mọi người cũng như cho chính bản thân chúng ta.Để khai phá ngọn nguồn mọi vấn đề cũng như giải pháp, bác sĩ Gawande đã theo chân một nữ y tá làm công việc chăm sóc bệnh nhân tại gia, phỏng vấn nhiều người trong giới bác sĩ lão khoa và sinh hoạt cùng họ, và tiếp xúc với những nhà quản lý viện dưỡng lão có tư tưởng cấp tiến và nhân văn. Ông tìm thấy những con người biết cách nói lên sự thật và chứng minh cho cả thế giới thấy, rằng mỗi người chúng ta đều có thể và có quyền mưu cầu cho mình một cuộc sống tốt đẹp và hạnh phúc bất chấp tuổi già sức yếu mà không phải hy sinh những giá trị sống mà chúng ta yêu quý hoặc tôn thờ.Với cách kể chuyện chân thực, sống động, mê hoặc và đánh động lòng người của tác giả, quyển sách Ai rồi cũng chết!khẳng định với chúng ta rằ Mỗi con người sinh ra không phải chỉ để ăn, ngủ hay tồn tại qua ngày, mà chính là để được sống một cuộc sống đúng nghĩa; rằng mục đích cuối cùng của y học không phải để kéo dài sự tồn tại vô nghĩa của con người, mà chính là để giúp chúng ta có một cuộc sống mãi mãi đong đầy hạnh phúc - cho đến tận phút lâm chung!

Jon Ronson meets David Grann in this fascinating, wildly entertaining adventure and travel story about how culture can make us go totally insaneThe Geography of Madness is an investigation of "culture-bound" syndromes, which are far stranger than they sound. Why is it, for example, that some men believe, against all reason, that vandals stole their penises, even though they're in good physical shape? In The Geography of Madness, acclaimed magazine writer Frank Bures travels around the world to trace culture-bound syndromes to their sources—and in the process, tells a remarkable story about the strange things all of us believe.Book Club Discussion Questions: For the paperback edition, a list of book club discussion questions is also being issued. If you’d like to add the The Geography of Madness to your group’s reading list, here are several conversation starters:1) One main themes of The Geography of Madness is that stories (about the world, about our lives, about our bodies) are contagious. Can you think of a story, or an experience, that changed what you believed was possible?2) Do you believe the brain and the mind are the same thing? If not, what is the difference? 3) The stories in The Geography of Madness raise the question of free will: How much do you choose the life you live? How much do you learn (or catch) you life choices from those around you? 4) Have you ever found yourself immersed in a situation where you did not know the rules? What was that like?5) In The Geography of Madness, the author argues that our mindset and our expectations have biological consequences. Does that resemble your experience? If so, how?6) Try to imagine living in a world where it was possible to have your genitals stolen, either by magic or by ghosts. How would you protect yourself?7) In The Geography of Madness, the author argues that a strong sense of self—of your story— can help to activate your endogenous (internal) healing systems and vice versa. Do you remember a time when a stressful or difficult period seemed to be followed by a health problem or sickness? 8) In The Geography of Madness, did anyone’s genital actually disappear? If not, what happened? Does it matter?9) Is there a belief that everyone around you holds, but that you don’t share? How did you come to doubt this?10) The Handbook of Depression points to a genetic marker associated with greater vulnerability to depression. Yet this link only holds true in Western cultures. Why would that be?11) Have you ever had a health problem you were afraid to talk about, or that others didn’t believe in?12) In The Geography of Madness, the author argues that cultural syndromes are “real” syndromes, but that their causes might not lie where we think they do. Do you think they are “real” or “imaginary”? 13) Over the last few years, gluten intolerance has been rising. This rise occurs at a time of increasing anxiety about the relationship between food, health and identity. What’s changed: our bodies or our culture?14) After reading The Geography of Madness, how would you describe what culture is?15) How much does a your culture create you? How much do you create your culture?16) Have you ever had a cultural syndrome?

The author of the New York Times bestseller Broken Open returns with a visceral and profound memoir of two sisters who, in the face of a bone marrow transplant—one the donor and one the recipient—begin a quest for acceptance, authenticity, and most of all, love.A mesmerizing and courageous the story of two sisters uncovering the depth of their love through the life-and-death experience of a bone marrow transplant. Throughout her life, Elizabeth Lesser has sought understanding about what it means to be true to oneself and, at the same time, truly connected to the ones we love. But when her sister Maggie needs a bone marrow transplant to save her life, and Lesser learns that she is the perfect match, she faces a far more immediate and complex question about what it really means to love—honestly, generously, and authentically.Hoping to give Maggie the best chance possible for a successful transplant, the sisters dig deep into the marrow of their relationship to clear a path to unconditional acceptance. They leave the bone marrow transplant up to the doctors, but take on what Lesser calls a "soul marrow transplant," examining their family history, having difficult conversations, examining old assumptions, and offering forgiveness until all that is left is love for each other’s true selves. Their process—before, during, and after the transplant—encourages them to take risks of authenticity in other aspects their lives.But life does not follow the storylines we plan for it. Maggie’s body is ultimately too weak to fight the relentless illness. As she and Lesser prepare for the inevitable, they grow ever closer as their shared blood cells become a symbol of the enduring bond they share. Told with suspense and humor, Marrow is joyous and heartbreaking, incandescent and profound. The story reveals how even our most difficult experiences can offer unexpected spiritual growth. Reflecting on the multifaceted nature of love—love of other, love of self, love of the world—Marrow is an unflinching and beautiful memoir about getting to the very center of ourselves.

From the best-selling author of Why We Get Fat, a groundbreaking, eye-opening expose that makes the convincing case that sugar is the tobacco of the new millennium: backed by powerful lobbies, entrenched in our lives, and making us very sick.Among Americans, diabetes is more prevalent today than ever; obesity is at epidemic proportions; nearly 10% of children are thought to have nonalcoholic fatty liver disease. And sugar is at the root of these, and other, critical society-wide, health-related problems. With his signature command of both science and straight talk, Gary Taubes delves into Americans' history with sugar: its uses as a preservative, as an additive in cigarettes, the contemporary overuse of high-fructose corn syrup. He explains what research has shown about our addiction to sweets. He clarifies the arguments against sugar, corrects misconceptions about the relationship between sugar and weight loss; and provides the perspective necessary to make informed decisions about sugar as individuals and as a society.

In the dying months of World War I, Spanish flu suddenly overwhelmed the world, killing between 50 and 100 million people.German soldiers termed it Blitzkatarrh, British soldiers called it Flanders Grippe, but globally the pandemic gained the notorious title of ‘Spanish Flu’.Nowhere escaped this common in Britain, 250,000 people died, in the United States it was 750,000, five times its total military fatalities in the war, while European deaths reached over two million. The numbers are staggering. And yet at the time, news of the danger was suppressed for fear of impacting war-time morale. Even today these figures are shocking to many – the war still hiding this terrifying menace in its shadow.And behind the numbers are human lives, stories of those who suffered and fought it – in the hospitals and laboratories. Catharine Arnold traces the course of the disease, its origins and progress, across the globe via these remarkable people. Some are well known to us, like British Prime Minister David Lloyd George, US President Woodrow Wilson, and writers Robert Graves and Vera Brittain, but many more are unknown. They are the doughboys from the US, gold miners in South Africa, schoolgirls in Great Britain and many others. Published 100 years after the most devastating pandemic in world history, Pandemic 1918 uses previously unpublished records, memoirs, diaries and government publications to uncover the human story of 1918.

A searing, deeply moving memoir of illness and recovery that traces one young woman’s journey from diagnosis to remission and, ultimately, a road trip of healing and self-discovery.In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter "the real world". She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone.It started with an itch - first on her feet, then up her legs, like 1,000 invisible mosquito bites. Next came the exhaustion, and the six-hour naps that only deepened her fatigue. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival. Just like that, the life she had imagined for herself had gone up in flames. By the time Jaouad flew home to New York, she had lost her job, her apartment, and her independence. She would spend much of the next four years in a hospital bed, fighting for her life and chronicling the saga in a column for The New York Times.When Jaouad finally walked out of the cancer ward - after three and a half years of chemo, a clinical trial, and a bone marrow transplant - she was, according to the doctors, cured. But as she would soon learn, a cure is not where the work of healing ends; it’s where it begins. She had spent the past 1,500 days in desperate pursuit of one goal - to survive. And now that she’d done so, she realized that she had no idea how to live.How would she reenter the world and live again? How could she reclaim what had been lost? Jaouad embarked - with her new best friend, Oscar, a scruffy terrier mutt - on a 100-day, 15,000-mile road trip across the country. She set out to meet some of the strangers who had written to her during her years in the hospital: a teenage girl in Florida also recovering from cancer; a teacher in California grieving the death of her son; a death-row inmate in Texas who’d spent his own years confined to a room. What she learned on this trip is that the divide between sick and well is porous, that the vast majority of us will travel back and forth between these realms throughout our lives. Between Two Kingdoms is a profound chronicle of survivorship and a fierce, tender, and inspiring exploration of what it means to begin again.

NEW YORK TIMES BESTSELLER • A must-read owner’s manual for every body. Take a head-to-toe tour of the marvel that is the human body in this “delightful, anecdote-propelled read” ( The Boston Globe ) from the author of A Short History of Nearly Everything . With a new Afterword.“You will marvel at the brilliance and vast weirdness of your design." — The Washington Post Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body—how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Brysonesque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular.As Bill Bryson writes, “We pass our existence within this wobble of flesh and yet take it almost entirely for granted.” The Body will cure that indifference with generous doses of wondrous, compulsively readable facts and information. As addictive as it is comprehensive, this is Bryson at his very best.

A gorgeously illustrated deep dive into the immune system that will forever change how you think about your body, from the creator of the popular science YouTube channel Kurzgesagt—In a NutshellYou wake up and feel a tickle in your throat. Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

Longlisted for the FT/McKinsey Business Book of the Year Award The authoritative account of the race to produce the vaccines that are saving us all, from the #1 New York Times bestselling author of The Man Who Solved the MarketFew were ready when a mysterious respiratory illness emerged in Wuhan, China in January 2020. Politicians, government officials, business leaders, and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world’s biggest drug and vaccine makers were slow to react or couldn’t muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist despised by his peers. Far from the limelight, each had spent years developing innovative vaccine approaches. Their work was met with skepticism and scorn. By 2020, these individuals had little proof of progress. Yet they and their colleagues wanted to be the ones to stop the virus holding the world hostage. They scrambled to turn their life’s work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough—and to beat each other for the glory that a vaccine guaranteed. A #1 New York Times bestselling author and award-winning Wall Street Journal investigative journalist, Zuckerman takes us inside the top-secret laboratories, corporate clashes, and high-stakes government negotiations that led to effective shots. Deeply reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It’s a story of courage, genius, and heroism. It’s also a tale of heated rivalries, unbridled ambitions, crippling insecurities, and unexpected drama. A Shot to Save the World is the story of how science saved the world.

Neuroscientist V.S. Ramachandran is internationally renowned for uncovering answers to the deep and quirky questions of human nature that few scientists have dared to address. His bold insights about the brain are matched only by the stunning simplicity of his experiments -- using such low-tech tools as cotton swabs, glasses of water and dime-store mirrors. In Phantoms in the Brain, Dr. Ramachandran recounts how his work with patients who have bizarre neurological disorders has shed new light on the deep architecture of the brain, and what these findings tell us about who we are, how we construct our body image, why we laugh or become depressed, why we may believe in God, how we make decisions, deceive ourselves and dream, perhaps even why we're so clever at philosophy, music and art. Some of his most notable cases:A woman paralyzed on the left side of her body who believes she is lifting a tray of drinks with both hands offers a unique opportunity to test Freud's theory of denial.A man who insists he is talking with God challenges us to ask: Could we be "wired" for religious experience?A woman who hallucinates cartoon characters illustrates how, in a sense, we are all hallucinating, all the time.Dr. Ramachandran's inspired medical detective work pushes the boundaries of medicine's last great frontier -- the human mind -- yielding new and provocative insights into the "big questions" about consciousness and the self.

On its initial publication, Forgive and Remember emerged as the definitive study of the training and lives of young surgeons. Now with an extensive new preface, epilogue, and appendix by the author, reflecting on the changes that have taken place since the book's original publication, this updated second edition of Charles L. Bosk's classic study is as timely as ever.

Neither a just say no treatise nor a how-to manual, this easy-to-read handbook is based on the conviction that the well-informed make better decisions. It provides information on how drugs enter the body, how they manipulate the brain, their short- & long-term effects, the high they produce & the circumstances in which they can be deadly. psychological & pharmacological research on drugs. Whether the reader is a student confronted by drugs for the first time, an accountant reaching for another cup of coffee, or a health educator, this book aims to provide a clear understanding of how drugs work & the consequences of their use.

Cholera was the classic epidemic disease of the nineteenth century, as the plague had been for the fourteenth. Its defeat was a reflection not only of progress in medical knowledge but of enduring changes in American social thought. Rosenberg has focused his study on New York City, the most highly developed center of this new society. Carefully documented, full of descriptive detail, yet written with an urgent sense of the drama of the epidemic years, this narrative is as absorbing for general audiences as it is for the medical historian. In a new Afterword, Rosenberg discusses changes in historical method and concerns since the original publication of The Cholera Years ."A major work of interpretation of medical and social thought . . . this volume is also to be commended for its skillful, absorbing presentation of the background and the effects of this dread disease."—I.B. Cohen, New York Times" The Cholera Years is a masterful analysis of the moral and social interest attached to epidemic disease, providing generally applicable insights into how the connections between social change, changes in knowledge and changes in technical practice may be conceived."—Steven Shapin, Times Literary Supplement"In a way that is all too rarely done, Rosenberg has skillfully interwoven medical, social, and intellectual history to show how medicine and society interacted and changed during the 19th century. The history of medicine here takes its rightful place in the tapestry of human history."—John B. Blake, Science

A fascinating account of vaccination's miraculous, inflammatory past and its uncertain future.In 1796, as smallpox ravaged Europe, Edward Jenner injected a child with a benign version of the disease, then exposed the child to the deadly virus itself. The boy proved resistant to smallpox, and Jenner's risky experiment produced the earliest vaccination. In this deftly written account, journalist Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy—from Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the twentieth century, and finally to the tumult currently surrounding vaccination.Faced with threats from anthrax to AIDS, we are a vulnerable population and can no longer depend on vaccines; numerous studies have linked childhood vaccination with various neurological disorders, and our pharmaceutical companies are more attracted to the profits of treatment than to the prevention of disease. With narrative grace and investigative journalism, Allen explores our shifting understanding of vaccination since its creation. 16 pages of illustrations.

To these seven paradoxical tales of neurological disorder and creativity, Oliver Sacks brings the profound compassion and ceaseless curiosity that made "Awakenings" and "The Man Who Mistook His Wife for a Hat" international bestsellers. He transports us into the uncanny worlds of his subjects, including an artist who loses his ability to see (or even imagine) color; a surgeon who performs delicate operations in spite of the compulsive tics and outbursts of Tourette's syndrome; and an autistic professor who holds a Ph.D. in animal science but is so bewildered by the complexity of human emotion that she feels "like an anthropologist on Mars."Through these extraordinary people, Sacks explores what it is to feel, to sense, to remember - to be, ultimately, a coherent self in the world.

I spent five years of my life being treated for cancer, but since then I've spent fifteen years being treated for nothing other than looking different from everyone else. It was the pain from that, from feeling ugly, that I always viewed as the great tragedy of my life. The fact that I had cancer seemed minor in comparison.At age nine, Lucy Grealy was diagnosed with a potentially terminal cancer. When she returned to school with a third of her jaw removed, she faced the cruel taunts of classmates. In this strikingly candid memoir, Grealy tells her story of great suffering and remarkable strength without sentimentality and with considerable wit. Vividly portraying the pain of peer rejection and the guilty pleasures of wanting to be special, Grealy captures with unique insight what it is like as a child and young adult to be torn between two warring impulses: to feel that more than anything else we want to be loved for who we are, while wishing desperately and secretly to be perfect.

Jill Taylor was a 37-year-old Harvard-trained brain scientist when a blood vessel exploded in her brain. Through the eyes of a curious scientist, she watched her mind deteriorate whereby she could not walk, talk, read, write, or recall any of her life. Because of her understanding of the brain, her respect for the cells in her body, and an amazing mother, Jill completely recovered. In My Stroke of Insight, she shares her recommendations for recovery and the insight she gained into the unique functions of the two halves of her brain. When she lost the skills of her left brain, her consciousness shifted away from normal reality where she felt "at one with the universe." Taylor helps others not only rebuild their brains from trauma, but helps those of us with normal brains better understand how we can consciously influence the neural circuitry underlying what we think, how we feel and how we react to life's circumstances.

An unforgettable, illuminating story of how men live and how they survive, from the acclaimed New York Times bestselling author of Cutting for Stone.When Abraham Verghese, a physician whose marriage is unraveling, relocates to El Paso, Texas, he hopes to make a fresh start as a staff member at the county hospital. There he meets David Smith, a medical student recovering from drug addiction, and the two men begin a tennis ritual that allows them to shed their inhibitions and find security in the sport they love and with each other. This friendship between doctor and intern grows increasingly rich and complex, more intimate than two men usually allow. Just when it seems nothing can go wrong, the dark beast from David’s past emerges once again—and almost everything Verghese has come to trust and believe in is threatened as David spirals out of control.

Anthrax. Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret. No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.

Sleep better, live longer with the groundbreaking information and step-by-step program in this revolutionary book.Healthful sleep has been empirically proven to be the single most important factor in predicting longevity, more influential than diet, exercise, or heredity. And yet we are a sleep-sick society, ignorant of the facts of sleep--and the price of sleep deprivation. In this groundbreaking book, based on decades of study on the frontiers of sleep science, Dr. William Dement, founder and director of the Stanford University Sleep Research Center, explains what happens when we sleep, when we don't, and how we can reclaim the most powerful--and underrated--health miracle of all. Taking us on a fascinating tour of our sleeping body and mind, Dr. Dement reveals the price we have paid for ignoring sleep--an epidemic of heart disease, 33 percent of traffic-fatigue-related accidents, and immeasurable mental and psychological disadvantages. And he offers a hands-on prescription for vibrant good health and longevity, including...self-tests to determine how much sleep you really need...the role of prescription and over-the-counter sleeping aids...the latest research on how sleep affects the immune system...how to combat insomnia, snoring, and jet lag...plus information on sleep disorder clinics nationwide, Web sites, and more.Taking readers on a fascinating tour of our sleeping body and mind, Dr. William C. Dement reveals the price paid for ignoring sleep--an epidemic of heart disease, traffic-fatigue-related accidents (responsible for a full third of all traffic accidents), and immeasurable mental and psychological disadvantages. Offering a hands-on prescription for vibrant good health and longevity, THE PROMISE OF SLEEP includes self-tests to determine how much sleep you really need, full information on the role of prescription and over-the-counter sleeping aids, the latest research on how sleep affects the immune system, helpful methods for combating insomnia, snoring, and jet lag, plus information on sleep disorder clinics nationwide, sleep disorder Web sites, and more. -->

We all worry. We all have moments of unfounded dread (Is someone behind that door?), or little phobias (roaches) or superstitions (step on a crack) that we indulge. Just Checking is an autobiographical account of what it is like to live with a full-blown case of obsessive-compulsive disorder (OCD), which, at its height, finds author Emily Colas nervous that she will contract a disease from blood that she sees on television. In the course of the book, what at first appear to her husband and friends to be Colas's idiosyncratic notions accumulate until she is frozen by the astounding psychological binds of OCD. Using precise (of course), connect-the-dots scenes, Colas draws a life that is at first highly monitored and ultimately unraveled by her disorder. One imagines that from afar, Colas's behavior at the height of her illness would look incomprehensible and just plain weird: She has to check the dishwasher multiple times before using it to make sure the cat is safe; the packaging of every new toothbrush has to meet rigorous sanitary standards; the landlord can't attempt to find new tenants for her apartment — she won't let them in the house. But readers are not at a distance here. Instead, we become privy to Colas's somewhat apologetic but firm explanations of what her logic was, and what it felt like to be afraid. She is so honest and witty that one can't help liking her, rooting for her, and wishing help would come. In a typical vignette, when the family tries to go to the Macy's Thanksgiving Day Parade ("definitely a mistake"), Colas is terrified that shewillstep on blood: When I was a kid in New York, all we had to eat on the street were pretzels and hot dogs. Food that was readily identifiable. Now, vendors sell the fanciest things with cherries, berries, jelly, and other crap that's way too close to the color of blood. We finally made it to where we had to go, but not before I had inspected the bottom of my shoes. There was a mushy red object there. Maybe a cherry, possibly a finger. The kids watched the parade on TV and I had a nice new worry. My kids don't even remember that lovely November day, but, lucky for me, I do. This event is sad and resonant, but it also manages to be viscerally entertaining. The result is that instead of inspiring schadenfreude, this book reminds us that psychological disorders are often exaggerations of the ordinary and familiar. We all, on a continuum, wish to survive, to avoid disease, to impose order on our lives. We sympathize with Colas's desperate attempts to find safety and with her seemingly loving husband's gradual loss of tolerance. Even the not-so-funny poems that are occasionally interspersed among the perfectly crafted chapterettes find their place. Strange as it may be to find charm in a memoir of illness, Colas is utterly winning. Hilary Liftin is a writer living in New York City. Her first book, coauthored with Kate Montgomery, is scheduled for publication by Vintage next year. She is the editorial development manager at BookWire (www.bookwire.com).

"In this landmark book, Robert O. Becker, M.D., a pioneer in the field of bioelectric science, presents a fascinating look at the role electricity plays in healing, challenging the traditional mechanistic model of the body. Colorful and controversial, this is a tale of engrossing research, scientific and medical politics, and breakthrough discoveries that offer new possibilities for fighting disease and harnessing the body's healing powers.

It's a prime ingredient in countless substances from cereal to soup, from cola to coffee. Consumed at the rate of one hundred pounds for every American every year, it's as addictive as nicotine -- and as poisonous. It's sugar. And "Sugar Blues", inspired by the crusade of Hollywood legend Gloria Swanson, is the classic, bestselling expose that unmasks our generation's greatest medical killer and shows how a revitalizing, sugar-free diet can not only change lives, but quite possibly save them.

Here David Oshinsky tells the gripping story of the polio terror and of the intense effort to find a cure, from the March of Dimes to the discovery of the Salk and Sabin vaccines--and beyond. Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

An entertaining and accessible look at the role of serendipity in major medical and scientific breakthroughs of the twentieth century explains how chance and lucky accidents led to the discovery of such medical advances as penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra.

The Divided Mind is the crowning achievement of Dr. John E. Sarno's distinguished career as a groundbreaking medical pioneer, going beyond pain to address the entire spectrum of psychosomatic (mindbody) disorders.The interaction between the generally reasonable, rational, ethical, moral conscious mind and the repressed feelings of emotional pain, hurt, sadness, and anger characteristic of the unconscious mind appears to be the basis for mindbody disorders. The Divided Mind traces the history of psychosomatic medicine, including Freud's crucial role, and describes the psychology responsible for the broad range of psychosomatic illness. The failure of medicine's practitioners to recognize and appropriately treat mindbody disorders has produced public health and economic problems of major proportions in the United States.One of the most important aspects of psychosomatic phenomena is that knowledge and awareness of the process clearly have healing powers. Thousands of people have become pain-free simply by reading Dr. Sarno's previous books. How and why this happens is a fascinating story, and is revealed in The Divided Mind.

IN THE WAR AGAINST DISEASES, THEY ARE THE SPECIAL FORCES. They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

In light of the health care crisis and the proliferation of HMOs, Dr. Weil has written a new introduction to this groundbreaking study of conventional and alternative medicine. Health and Healing presents the spectrum of alternative healing practices—holistic medicine, homeopathy, osteopathy, chiropractic, Chinese medicine—and outlines how they differ from conventional medicine.

Given the tensions and demands of medicine, highly successful physicians and surgeons rarely achieve equal success as prose writers. It is truly extraordinary that a major, international pioneer in the controversial field of transplant surgery should have written a spellbinding, and heart-wrenching, autobiography. Thomas Starzl grew up in LeMars, Iowa, the son of a newspaper publisher and a nurse. His father also wrote science fiction and was acquainted with the writer Ray Bradbury. Starzl left the family business to enter Northwestern University Medical School where he earned both and M.D. and a PhD. While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world’s first transplantation of the human liver in 1963. Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy. His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation. In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients. There are many heroes in the story of transplantation, and many “puzzle people,” the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts. They are old and young, obscure and world famous. Some have been taken into the hearts of America, like Stormie Jones, the brave and beautiful child from Texas. Every patient who receives someone else’s organ - and Starzl remembers each one - is a puzzle. “It was not just the acquisition of a new part,” he writes. “The rest of the body had to change in many ways before the gift could be accepted. It was necessary for the mind to see the world in a different way.” The surgeons and physicians who pioneered transplantation were also they too became puzzle people. “Some were corroded or destroyed by the experience, some were sublimated, and none remained the same.”

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they’ve transformed - people whose mental limitations or brain damage were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

“Amazing….Explores human courage under the most trying circumstances.” —New York Post “An inspirational story about business, medical science, and one father’s refusal to give up hope.” —Boston Globe The book that inspired the movie, Extraordinary Measures, starring Harrison Ford, Brendan Fraser, and Keri Russell, The Cure by Pulitzer Prize-winning journalist Geeta Anand is the remarkable true story of one father’s determination to find a cure for his terminally sick children even if it meant he had to build a business from scratch to do so. At once a riveting story of the birth of an enterprise—ala Tracy Kidder’s The Soul of a New Machine—and a inspiring tale of the indomitable human spirit in the vein of Erin Brockovich and A Civil Action, The Cure is a testament to ingenuity, unflagging will, and unconquerable love.

For centuries, parasites have lived in nightmares, horror stories, and in the darkest shadows of science. Now award-winning writer Carl Zimmer takes us on a fantastic voyage into the secret parasite universe we actually live in but haven't recognized. He reveals not only that parasites are the most successful life-forms on Earth, but that they triggered the development of sex, shape ecosystems, and have driven the engine of evolution. In mapping the parasite universe, Zimmer makes the astonishing observation that most species are parasites, and that almost every animal, including humans, will at one time or another become the home of a parasite. Zimmer shows how highly evolved parasites are and describes the frightening and amazing ingenuity these commando invaders use to devour their hosts from the inside and control their behavior. The sinister Sacculina carcini makes its home in an unlucky crab and proceeds to eat everything but what the crab needs to put food in its mouth, which Sacculina then consumes. When Sacculina finally reproduces, it places its young precisely where the crab would nurture its own progeny, and then has the crab nurture the foster family members. Single-celled Toxoplasma gondi has an even more insidious role, for it can invade the human brain. There it makes men distrustful and less willing to submit to social mores. Women become more outgoing and warm-hearted. Why would a parasite cause these particular personality changes? It seems Toxoplasma wants its host to be less afraid, to be more prone to danger and a violent end -- so that, in the carnage, it will be able to move on to another host. From the steamy jungles of Costa Rica to the fetid parasite heaven of rebel-held southern Sudan, Zimmer tracks the genius of parasitic life and its impact on humanity. We hosts have developed remarkable defenses against the indomitable parasite: our mighty immune system, our culturally enforced habit of keeping clean, and, perhaps most intriguingly, sex. But this is not merely a book about the evil power of parasitism and how we must defend against it. On the contrary, Zimmer concludes that humankind itself is a new kind of parasite, one that preys on the entire Earth. If we are to achieve the sophistication of the parasites on display here in vivid detail, if we are to promote the flourishing of life in all its diversity as they do, we must learn the ways nature lives with itself, the laws of Parasite Rex.

Must children born with socially challenging anatomies have their bodies changed because others cannot be expected to change their minds? One of Us views conjoined twinning and other "abnormalities" from the point of view of people living with such anatomies, and considers these issues within the larger historical context of anatomical politics. Anatomy matters, Alice Domurat Dreger tells us, because the senses we possess, the muscles we control, and the resources we require to keep our bodies alive limit and guide what we experience in any given context. Her deeply thought-provoking and compassionate work exposes the breadth and depth of that context--the extent of the social frame upon which we construct the "normal." In doing so, the book calls into question assumptions about anatomy and normality, and transforms our understanding of how we are all intricately and inextricably joined.

The Mind of a Mnemonist is a rare phenomenon - a scientific study that transcends its data and, in the manner of the best fictional literature, fashions a portrait of an unforgettable human being."

Today a brain scan reveals our thoughts, moods, and memories as clearly as an X-ray reveals our bones. We can actually observe a person's brain registering a joke or experiencing a painful memory. Drawing on the latest imaging technology and the expertise of distinguished scientists, Rita Carter explores the geography of the human brain. Her writing is clear, accessible, witty, and the book's 150 illustrations—most in color—present an illustrated guide to that wondrous, coconut-sized, wrinkled gray mass we carry inside our heads.Mapping the Mind charts the way human behavior and culture have been molded by the landscape of the brain. Carter shows how our personalities reflect the biological mechanisms underlying thought and emotion and how behavioral eccentricities may be traced to abnormalities in an individual brain. Obsessions and compulsions seem to be caused by a stuck neural switch in a region that monitors the environment for danger. Addictions stem from dysfunction in the brain's reward system. Even the sense of religious experience has been linked to activity in a certain brain region. The differences between men and women's brains, the question of a "gay brain," and conditions such as dyslexia, autism, and mania are also explored.Looking inside the brain, writes Carter, we see that actions follow from our perceptions, which are due to brain activity dictated by a neuronal structure formed from the interplay between our genes and the environment. Without sidestepping the question of free will, Carter suggests that future generations will use our increasing knowledge of the brain to "enhance those mental qualities that give sweetness and meaning to our lives, and to eradicate those that are destructive."

Few of the great stories of medicine are as palpably dramatic as the invention of open-heart surgery, yet, until now, no journalist has ever brought all of the thrilling specifics of this triumph to life.This is the story of the surgeon many call the father of open-heart surgery, Dr. C. Walton Lillehei, who, along with colleagues at University Hospital in Minneapolis and a small band of pioneers elsewhere, accomplished what many experts considered to be an impossible feat: He opened the heart, repaired fatal defects, and made the miraculous routine.Acclaimed author G. Wayne Miller draws on archival research and exclusive interviews with Lillehei and legendary pioneers such as Michael DeBakey and Christiaan Barnard, taking readers into the lives of these doctors and their patients as they progress toward their landmark achievement. In the tradition of works by Richard Rhodes and Tracy Kidder, King of Hearts tells the story of an important and gripping piece of forgotten science history.

When Rats, Lice and History appeared in 1935, Hans Zinsser was a highly regarded Harvard biologist who had never written about historical events. Although he had published under a pseudonym, virtually all of his previous writings had dealt with infections and immunity and had appeared either in medical and scientific journals or in book format. Today he is best remembered as the author of Rats, Lice, and History , which gone through multiple editions and remains a masterpiece of science writing for a general readership. To Zinsser, scientific research was high adventure and the investigation of infectious disease, a field of battle. Yet at the same time he maintained a love of literature and philosophy. His goal in Rats, Lice and History was to bring science, philosophy, and literature together to establish the importance of disease, and especially epidemic infectious disease, as a major force in human affairs. Zinsser cast his work as the "biography" of a disease. In his view, infectious disease simply represented an attempt of a living organism to survive. From a human perspective, an invading pathogen was abnormal; from the perspective of the pathogen it was perfectly normal. This book is devoted to a discussion of the biology of typhus and history of typhus fever in human affairs. Zinsser begins by pointing out that the louse was the constant companion of human beings. Under certain conditions–to wash or to change clothing–lice proliferated. The typhus pathogen was transmitted by rat fleas to human beings, who then transmitted it to other humans and in some strains from human to human. Rats, Lice and History is a tour de force. It combines Zinsser's expertise in biology with his broad knowledge of the humanities

Level 4: Virus Hunters of the CDC, is a memoir by America's most famous virus researchers. "Level 4" is the highest degree of laboratory containment for isolation and experimentation on microbiological organisms. Level-4 organisms produce lethal illnesses in humans and, for the most part, have no treatment and no prevention. Among the most infamous are the hemorrhagic viral diseases Ebola and Lassa Fever.This is the story of those who hunt the emerging diseases making global headlines. Join husband-and-wife team Dr. Joseph B. McCormick and Dr. Susan Fisher-Hoch in their search for those who may be infected by these lethal viruses. You will travel through equatorial Africa, the ghettos and rainforests of Brazil, and through settlements in northern Pakistan. Both Dr. McCormick and Dr. Fisher-Hoch will offer their scientific knowledge about how and why these viruses are so lethal to humans and what can be done to prevent any kind of devastating epidemic from ever breaking out. The book shows how dedication, intelligence and courage can prevail--and give us hope for the future of global health. 1570362777 , 978-1570362774

The definitive account of epidemics in our time, from the Pulitzer Prize-winning public heath expert Laurie Garrett.A New York Times notable bookUnpurified drinking water. Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

One of the nation's leading surgeons tells of his experiments that are revolutionizing the treatment of cancer. After meeting a man whose inoperable cancer spontaneously and mysteriously disappeared in 1968, Dr. Rosenberg began his quest for a cure for cancer. A rare view of the trials and triumphs of scientific discovery.

The struggle to perform well is universal: each one of us faces fatigue, limited resources, and imperfect abilities in whatever we do. But nowhere is this drive to do better more important than in medicine, where lives are on the line with every decision. In his new book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable. Gawande's gripping stories of diligence, ingenuity, and what it means to do right by people take us to battlefield surgical tents in Iraq, to labor and delivery rooms in Boston, to a polio outbreak in India, and to malpractice courtrooms around the country. He discusses the ethical dilemmas of doctors participation in lethal injections, examines the influence of money on modern medicine, and recounts the astoundingly contentious history of hand washing. And as in all his writing, Gawande gives us an inside look at his own life as a practicing surgeon, offering a searingly honest firsthand account of work in a field where mistakes are both unavoidable and unthinkable. At once unflinching and compassionate, Better is an exhilarating journey narrated by arguably the best nonfiction doctor-writer around (Salon). Gawande's investigation into medical professionals and how they progress from merely good to great provides rare insight into the elements of success, illuminating every area of human endeavor.

The hilarious novel of the healing arts that reveals everything your doctor never wanted you to know. Six eager interns—they saw themselves as modern saviors-to-be. They came from the top of their medical school class to the bottom of the hospital staff to serve a year in the time-honored tradition, racing to answer the flash of on-duty call lights and nubile nurses. But only the Fat Man—the Clam, all-knowing resident—could sustain them in their struggle to survive, to stay sane, to love and even to be doctors when their harrowing year was done.

“It manages to delight, and frequently to entrance, old and new readers [and] continues to engage our hearts and minds today with an indescribably brand of affectionate sympathy.”—F. Gonzalez-Crussi, from the IntroductionAn international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

Awakenings is a 1973 non-fiction book by Oliver Sacks. It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital in the Bronx, New York.

In this fresh approach to the history of the Black Death, world-renowned scholar John Hatcher re-creates everyday life in a mid-fourteenth century rural English village. By focusing on the experiences of ordinary villagers as they lived-and died-during the Black Death (1345-50), Hatcher vividly places the reader directly inside those tumultuous times and describes in fascinating detail the day-to-day existence of people struggling with the tragic effects of the plague. Dramatic scenes portray how contemporaries must have felt and thought about these momentous events: what they knew and didn't know about the horrors of the disease, what they believed about death and God's vengeance, and how they tried to make sense of it all despite frantic rumors, frightening tales, and fearful sermons.

The first edition of Jim Watson's classic textbook Molecular Biology of the Gene appeared in 1965. This new edition, written with five new authors, has been brought fully up to date, and incorporates insights very recently derived from genome sequencing in a variety of organisms. The book isan authoritative and comprehensive survey of the fundamentals of molecular biology, from basic mechanisms to the elaborate role of gene regulation in embryonic development and evolution. Although updated, the twentyDSone chapters of the new edition retain the distinctive and celebrated features ofthe original work, including introductory chapters on the history of genetics and molecular biology and an emphasis throughout on the chemical underpinnings of molecular biology. The new team of authors brings to this edition awardDSwinning teaching experience and outstanding research achievements.By revealing the intellectual framework and experimental approaches that made new discoveries in the field possible, the new edition highlights the significance of the molecular approach for all of biology.

For more than 3000 years, hundreds of millions of people have died or been left permanently scarred or blind by the relentless, incurable disease called smallpox. In 1967, Dr. D.A. Henderson became director of a worldwide campaign to eliminate this disease from the face of the earth.This spellbinding book is Dr. Henderson’s personal story of how he led the World Health Organization’s campaign to eradicate smallpox—the only disease in history to have been deliberately eliminated. Some have called this feat "the greatest scientific and humanitarian achievement of the past century."In a lively, engrossing narrative, Dr. Henderson makes it clear that the gargantuan international effort involved more than straightforward mass vaccination. He and his staff had to cope with civil wars, floods, impassable roads, and refugees as well as formidable bureaucratic and cultural obstacles, shortages of local health personnel and meager budgets. Countries across the world joined in the effort; the United States and the Soviet Union worked together through the darkest cold war days; and professionals from more than 70 nations served as WHO field staff. On October 26, 1976, the last case of smallpox occurred. The disease that annually had killed two million people or more had been vanquished–and in just over ten years.The story did not end there. Dr. Henderson recounts in vivid detail the continuing struggle over whether to destroy the remaining virus in the two laboratories still that held it. Then came the startling discovery that the Soviet Union had been experimenting with smallpox virus as a biological weapon and producing it in large quantities. The threat of its possible use by a rogue nation or a terrorist has had to be taken seriously and Dr. Henderson has been a central figure in plans for coping with it.New methods for mass smallpox vaccination were so successful that he sought to expand the program of smallpox immunization to include polio, measles, whooping cough, diphtheria, and tetanus vaccines. That program now reaches more than four out of five children in the world and is eradicating poliomyelitis.This unique book is to be treasured—a personal and true story that proves that through cooperation and perseverance the most daunting of obstacles can be overcome.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

In recent years, malaria has emerged as a cause célèbre for voguish philanthropists. Bill Gates, Bono, and Laura Bush are only a few of the personalities who have lent their names—and opened their pocketbooks—in hopes of curing the disease. Still, in a time when every emergent disease inspires waves of panic, why aren’t we doing more to eradicate one of our oldest foes? And how does a parasitic disease that we’ve known how to prevent for more than a century still infect 500 million people every year, killing nearly 1 million of them?In The Fever , the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we’ve invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria’s jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.

A story of courage and risk-taking, House on Fire tells how smallpox, a disease that killed, blinded, and scarred millions over centuries of human history, was completely eradicated in a spectacular triumph of medicine and public health. Part autobiography, part mystery, the story is told by a man who was one of the architects of a radical vaccination scheme that became a key strategy in ending the horrible disease when it was finally contained in India. In House on Fire, William H. Foege describes his own experiences in public health and details the remarkable program that involved people from countries around the world in pursuit of a single objective—eliminating smallpox forever. Rich with the details of everyday life, as well as a few adventures, House on Fire gives an intimate sense of what it is like to work on the ground in some of the world’s most impoverished countries—and tells what it is like to contribute to programs that really do change the world.

Humanity is on the cusp of an exciting longevity revolution. The first person to live to 150 years has probably already been born. What will your life look like when you live to be over 100? Will you be healthy? Will your marriage need a sunset clause? How long will you have to work? Will you finish one career at sixty-five only to go back to school to learn a new one? And then, will you be happily working for another sixty years? Maybe you’ll be a parent to a newborn and a grandparent at the same time. Will the world become overpopulated? And how will living longer affect your finances, your family life, and your views on religion and the afterlife? In 100 Plus, futurist Sonia Arrison takes us on an eye-opening journey to the future at our doorsteps, where science and technology are beginning to radically change life as we know it. She introduces us to the people transforming our lives: the brilliant scientists and genius inventors and the billionaires who fund their work. The astonishing advances to extend our lives—and good health—are almost here. In the very near future fresh organs for transplants will be grown in laboratories, cloned stem cells will bring previously unstoppable diseases to their knees, and living past 100 will be the rule, not the exception. Sonia Arrison brings over a decade of experience researching and writing about cutting-edge advances in science and technology to 100 Plus, painting a vivid picture of a future that only recently seemed like science fiction, but now is very real. 100 Plus is the first book to give readers a comprehensive understanding of how life-extending discoveries will change our social and economic worlds. This illuminating and indispensable text will help us navigate the thrilling journey of life beyond 100 years.

Viruses are the smallest living things known to science, yet they hold the entire planet in their sway. We are most familiar with the viruses that give us colds or the flu, but viruses also cause a vast range of other diseases, including one disorder that makes people sprout branch-like growths as if they were trees. Viruses have been a part of our lives for so long, in fact, that we are actually part virus: the human genome contains more DNA from viruses than our own genes. Meanwhile, scientists are discovering viruses everywhere they look: in the soil, in the ocean, even in caves miles underground.This fascinating book explores the hidden world of viruses—a world that we all inhabit. Here Carl Zimmer, popular science writer and author of Discover magazine’s award-winning blog The Loom, presents the latest research on how viruses hold sway over our lives and our biosphere, how viruses helped give rise to the first life-forms, how viruses are producing new diseases, how we can harness viruses for our own ends, and how viruses will continue to control our fate for years to come. In this eye-opening tour of the frontiers of biology, where scientists are expanding our understanding of life as we know it, we learn that some treatments for the common cold do more harm than good; that the world’s oceans are home to an astonishing number of viruses; and that the evolution of HIV is now in overdrive, spawning more mutated strains than we care to imagine.The New York Times Book Review calls Carl Zimmer “as fine a science essayist as we have.” A Planet of Viruses is sure to please his many fans and further enhance his reputation as one of America’s most respected and admired science journalists.

How shall we improve human health? One answer by eradication. The Gates Foundation announced in 2007 that their goal is malaria eradication; another of their priorities is polio eradication. Eradication means the complete elimination of a disease through deliberate human intervention. It stands for an absolute in public health. This book by the award-winning historian of medicine Nancy Leys Stepan is an accessible, beautifully written, and deeply researched examination of one of the most controversial issues in public health today. The eradication of disease might seem like an absolute good. But critics of eradication argue that the huge resources needed to achieve eradication could be better allocated toward developing primary health services and general improvement in health. This book aims to look at the benefits and drawbacks of single-minded efforts to rid the world of particular diseases, one at a time. The sweep of the book is impressive, from the origins of the idea of complete eradication in the early twentieth century until the present-day campaigns against polio, Guinea worm disease, and now malaria. The author places eradication's story in its many contexts, from imperialism, changing notions of public health, the history of medicine and its technologies, the development of international health agencies such as the World Health Organization, and the impact of the Cold War on the shift of attention to disease in developing countries. At the center of this narrative is Dr. Fred Lowe Soper (1893-1977), a U.S.-trained doctor who became the arch-eradicationist of his time. His campaigns to eradicate hookworm disease, yaws, yellow fever, malaria, and smallpox are treated in compelling detail, as are the roles of international health agencies such as the Rockefeller Foundation and the World Health Organization. Throughout the book Stepan draws attention to the way that the ideal of eradication has repeatedly arisen, phoenix-like, from its setbacks. In a powerful conclusion, she uses the example of the current campaign to eradicate Guinea worm disease to argue that, today, under the right circumstances, eradication and primary health care need not be in conflict, as they were in the past, but can form mutually reinforcing policies to improve the health and well-being of populations, especially the poorest and most disease-burdened populations of the world.

From Pulitzer Prize winner Amanda Bennett comes a moving, eye-opening, and beautifully written memoir—a love story of two unusual people, their complex marriage and deep devotion, and finally, Bennett’s quest to save her husband’s life. When Wall Street Journal reporter Amanda Bennett meets the eccentric, infuriating, yet somehow irresistible Terence Bryan Foley while on assignment in China, the last thing she expects is to marry him. They are so different—classic and bohemian, bow ties and batik, quirky and sensible. But Terence is persistent. “You are going to be somebody,” he tells her. “You’re going to need somebody to take care of you.” Though initially as combative as their courtship, their marriage brings with it stormy passion, deep love and respect, two beloved children, and a life together over two decades. Then comes illness, and the fight to win a longer life for Terence. The Cost of Hope chronicles the extraordinary measures Amanda and Terence take to preserve not only Terence’s life but also the life of their family. After his death, Bennett uses her skills as a veteran investigative reporter to determine the cost of their mission of hope. What she discovers raises important questions many people face, and vital issues about the intricacies of America’s healthcare system. Rich in humor, insight, and candor, The Cost of Hope is an unforgettable memoir, an inspiring personal story that sheds light on one of the most important turning points in life.

Ebola, SARS, Hendra, AIDS, and countless other deadly viruses all have one thing in common: the bugs that transmit these diseases all originate in wild animals and pass to humans by a process called spillover. In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

A visionary and completely original investigation that will change the way we think about health care: how and why it is failing, why expanding insurance coverage will only make things worse, and how it can be transformed into a transparent, affordable, successful system.In 2007, David Goldhill's father died from a series of infections acquired in a well-regarded New York hospital. The bill was for several hundred thousand dollars--and Medicare paid it. These circumstances left Goldhill angry and determined to understand how it was possible that world-class technology and well-trained personnel could result in such simple, inexcusable carelessness--and how a business that failed so miserably could be rewarded with full payment. Catastrophic Care is the eye-opening result. Goldhill explicates a health-care system that now costs nearly $2.5 trillion annually, bars many from treatment, provides inconsistent quality of care, offers negligible customer service, and in which an estimated 200,000 Americans die each year from errors. Above all, he exposes the fundamental fallacy of our entire system--that Medicare and insurance coverage make care cheaper and improve our health--and suggests a comprehensive new approach that could produce better results at more acceptable costs immediately by giving us, the patients, a real role in the process.

From #1 New York Times bestselling author Dr. Perlmutter, the devastating truth about the effects of wheat, sugar, and carbs on the brain, and a 4-week plan to achieve optimum health.In Grain Brain, renowned neurologist David Perlmutter, MD, blows the lid off a finding that's been buried in medical literature for far too long: carbs are destroying your brain. Even so-called healthy carbs like whole grains can cause dementia, ADHD, anxiety, chronic headaches, depression, decreased libido, and much more. Groundbreaking and timely, Grain Brain shows that the fate of your brain is not in your genes, it's in the food you eat. Dr. Perlmutter explains what happens when your brain encounters common ingredients in fruit bowls and bread, how statins may be erasing your memory, why a diet high in "good fats" is ideal, and how to spur the growth of new brain cells at any age. And his revolutionary 4-week plan will show you how to keep your brain healthy and sharp while dramatically reducing your risk for debilitating neurological disease -- without drugs. Featuring a blend of cutting-edge research, real-life stories of transformation, and accessible, practical advice, Grain Brain teaches you how to take control of your "smart genes," regain wellness, and enjoy lifelong health and vitality.

In the tradition of the best investigative journalism, physician and reporter Sheri Fink reconstructs 5 days at Memorial Medical Center and draws the reader into the lives of those who struggled mightily to survive and to maintain life amid chaos.After Katrina struck and the floodwaters rose, the power failed, and the heat climbed, exhausted caregivers chose to designate certain patients last for rescue. Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

A landmark book of popular science—a lucid, engaging account of how the human body evolved over millions of years and of how the increasing disparity between the jumble of adaptations in our Stone Age bodies and the modern world is fueling the paradox of greater longevity but more chronic disease. In a book that illuminates, as never before, the evolutionary story of the human body, Daniel Lieberman deftly examines the major transformations that contributed key adaptations to the body: the advent of bipedalism; the shift to a non-fruit-based diet; the rise of hunting and gathering and our superlative endurance athletic abilities; the development of a very large brain; and the incipience of modern cultural abilities. He elucidates how cultural evolution differs from biological evolution, and how it further transformed our bodies during the Agricultural and Industrial Revolutions. Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

The definitive story of American health care today -- its causes, consequences, and confusions. In March 2010, the Affordable Care Act was signed into law. It was the most extensive reform of America's health care system since at least the creation of Medicare in 1965, and maybe ever. The ACA was controversial and highly political, and the law faced legal challenges reaching all the way to the Supreme Court; it even precipitated a government shutdown. It was a signature piece of legislation for President Obama's first term, and also a ball and chain for his second. Ezekiel J. Emanuel, a professor of medical ethics and health policy at the University of Pennsylvania who also served as a special adviser to the White House on health care reform, has written a brilliant diagnostic explanation of why health care in America has become such a divisive social issue, how money and medicine have their own -- quite distinct -- American story, and why reform has bedeviled presidents of the left and right for more than one hundred years. Emanuel also explains exactly how the ACA reforms are reshaping the health care system now. He forecasts the future, identifying six mega trends in health that will determine the market for health care to 2020 and beyond. His predictions are bold, provocative, and uniquely well-informed. Health care -- one of America's largest employment sectors, with an economy the size of the GDP of France -- has never had a more comprehensive or authoritative interpreter.

NEW YORK TIMES BESTSELLER The New York Times –bestselling author of The Brain That Changes Itself presents astounding advances in the treatment of brain injury and illness. Now in an updated and expanded paperback edition.Winner of the 2015 Gold Nautilus Book Award in Science & CosmologyIn his groundbreaking work The Brain That Changes Itself , Norman Doidge introduced readers to neuroplasticity—the brain’s ability to change its own structure and function in response to activity and mental experience. Now his revolutionary new book shows how the amazing process of neuroplastic healing really works. The Brain’s Way of Healin g describes natural, noninvasive avenues into the brain provided by the energy around us—in light, sound, vibration, and movement—that can awaken the brain’s own healing capacities without producing unpleasant side effects. Doidge explores cases where patients alleviated chronic pain; recovered from debilitating strokes, brain injuries, and learning disorders; overcame attention deficit and learning disorders; and found relief from symptoms of autism, multiple sclerosis, Parkinson’s disease, and cerebral palsy. And we learn how to vastly reduce the risk of dementia, with simple approaches anyone can use. For centuries it was believed that the brain’s complexity prevented recovery from damage or disease. The Brain’s Way of Healing shows that this very sophistication is the source of a unique kind of healing. As he did so lucidly in The Brain That Changes Itself , Doidge uses stories to present cutting-edge science with practical real-world applications, and principles that everyone can apply to improve their brain’s performance and health.

All of us have a most remarkable gene lurking in our DNA. Its job is to protect us from cancer. This gene, known simply as p53, constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process, p53 repairs it before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history.p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time—the groundbreaking program to answer the most essential question for humanity: how do we live and die?—and the visionary mastermind behind it.Medical doctor and economist Christopher Murray began the Global Burden of Disease studies to gain a truer understanding of how we live and how we die. While it is one of the largest scientific projects ever attempted—as breathtaking as the first moon landing or the Human Genome Project—the questions it answers are meaningful for every one of us: What are the world’s health problems? Who do they hurt? How much? Where? Why?Murray argues that the ideal existence isn’t simply the longest but the one lived well and with the least illness. Until we can accurately measure how people live and die, we cannot understand what makes us sick or do much to improve it. Challenging the accepted wisdom of the WHO and the UN, the charismatic and controversial health maverick has made enemies—and some influential friends, including Bill Gates who gave Murray a $100 million grant.In Epic Measures, journalist Jeremy N. Smith offers an intimate look at Murray and his groundbreaking work. From ranking countries’ healthcare systems (the U.S. is 37th) to unearthing the shocking reality that world governments are funding developing countries at only 30% of the potential maximum efficiency when it comes to health, Epic Measures introduces a visionary leader whose unwavering determination to improve global health standards has already changed the way the world addresses issues of health and wellness, sets policy, and distributes funding.

A masterful synchronization of history and cutting-edge science shines new light on humanities darkest diagnosis.In the wake of the Cancer Genome Atlas project's failure to provide a legible roadmap to a cure for cancer, science writer Travis Christofferson illuminates a promising blend of old and new perspectives on the disease. Tripping over the Truth follows the story of cancers proposed metabolic origin from the vaunted halls of the German scientific golden age, to modern laboratories around the world. The reader is taken on a journey through time and science that results in an unlikely connecting of the dots with profound therapeutic implications.Transporting us on a rich narrative of humanities struggle to understand the cellular events that conspire to form malignancy, it reads like a detective novel, full of twists and cover-ups, blind-alleys and striking moments of discovery by men and women with uncommon vision, grit and fortitude. Ultimately we arrive at a conclusion that challenges everything we thought we knew about the disease, suggesting the reason for the failed war against cancer stems from a flawed paradigm that categorizes cancer as an exclusively genetic disease. For anyone affected by this terrifying disease, and the physicians who struggle to treat it, Tripping Over the Truth provides a fresh and hopeful perspective. It explores the new and exciting non-toxic therapies born from the emerging metabolic theory of cancer. Therapies that may one day prove to be a turning point in the struggle against our ancient enemy. We are shown how the metabolic theory redraws the battle-map, directing researchers to approach cancer treatment from a different angle, framing it more like a gentle rehabilitation rather than all-out combat. In a sharp departure from the current "targeted" revolution occurring in cancer pharmaceuticals, the metabolic therapies highlighted have one striking feature that sets them apart -the potential to treat all types of cancer because they exploit the one weakness that is common to every cancer cell: dysfunctional metabolism.

INTERNATIONAL BESTSELLER • A “wonderful memoir” ( Los Angeles Times ) about a brilliantly unconventional physician and writer, a man who has illuminated the many ways that the brain makes us human. • “Intimate.... Brim[s] with life and affection.” — The New York TimesWhen Oliver Sacks was twelve years old, a perceptive schoolmaster “Sacks will go far, if he does not go too far.” It is now abundantly clear that Sacks has never stopped going. With unbridled honesty and humor, Sacks writes about the passions that have driven his life—from motorcycles and weight lifting to neurology and poetry. He writes about his love affairs, both romantic and intellectual; his guilt over leaving his family to come to America; his bond with his schizophrenic brother; and the writers and scientists—W. H. Auden, Gerald M. Edelman, Francis Crick—who have influenced his work.

Growing up in the high desert of California, Jim Doty was poor, with an alcoholic father and a mother chronically depressed and paralyzed by a stroke. Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.

Every animal, whether human, squid, or wasp, is home to millions of bacteria and other microbes. Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster, not only of the twentieth century, but possibly in all of recorded history. And yet, in our popular conception it exists largely as a footnote to World War I.In Pale Rider, Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain, and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered; and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.Laura Spinney writes that the Spanish flu was as significant – if not more so – as two world wars in shaping the modern world; in disrupting, and often permanently altering, global politics, race relations, family structures, and thinking across medicine, religion and the arts.

At a moment of drastic political upheaval, An American Sickness is a shocking investigation into our dysfunctional healthcare system - and offers practical solutions to its myriad problems.In these troubled times, perhaps no institution has unraveled more quickly and more completely than American medicine. In only a few decades, the medical system has been overrun by organizations seeking to exploit for profit the trust that vulnerable and sick Americans place in their healthcare. Our politicians have proven themselves either unwilling or incapable of reining in the increasingly outrageous costs faced by patients, and market-based solutions only seem to funnel larger and larger sums of our money into the hands of corporations. Impossibly high insurance premiums and inexplicably large bills have become facts of life; fatalism has set in. Very quickly Americans have been made to accept paying more for less. How did things get so bad so fast?Breaking down this monolithic business into the individual industries--the hospitals, doctors, insurance companies, and drug manufacturers--that together constitute our healthcare system, Rosenthal exposes the recent evolution of American medicine as never before. How did healthcare, the caring endeavor, become healthcare, the highly profitable industry? Hospital systems, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Patients receive bills in code, from entrepreneurial doctors they never even saw.The system is in tatters, but we can fight back. Dr. Elisabeth Rosenthal doesn't just explain the symptoms, she diagnoses and treats the disease itself. In clear and practical terms, she spells out exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship and to hospital C-suites, explaining step-by-step the workings of a system badly lacking transparency. This is about what we can do, as individual patients, both to navigate the maze that is American healthcare and also to demand far-reaching reform. An American Sickness is the frontline defense against a healthcare system that no longer has our well-being at heart.

Too many Americans are taking too many drugs—and it's costing us our health, happiness, and lives.Prescription drug use in America has increased tenfold in the past 50 years, and over-the-counter drug use has risen just as dramatically. In addition to the dozens of medications we take to treat serious illnesses, we take drugs to help us sleep, to keep us awake, to keep our noses from running, our backs from aching, and our minds from racing. Name a symptom, there's a pill to suppress it.Modern drugs can be miraculously life-saving, and many illnesses demand their use. But what happens when our reliance on powerful pharmaceuticals blinds us to their risks? Painful side effects and dependency are common, and adverse drug reactions are America's fourth leading cause of death.In Mind Over Meds, bestselling author Dr. Andrew Weil alerts readers to the problem of overmedication, and outlines when medicine is necessary, and when it is not. Dr. Weil examines how we came to be so drastically overmedicated, presents science that proves drugs aren't always the best option, and provides reliable integrative medicine approaches to treating common ailments like high blood pressure, allergies, depression, and even the common cold. With case histories, healthy alternative treatments, and input from other leading physicians, Mind Over Meds is the go-to resource for anyone who is sick and tired of being sick and tired.

Can what you eat determine how long, and how well, you live? The clinically proven answer is yes, and The Longevity Diet is easier to follow than you'd think. The culmination of 25 years of research on aging, nutrition, and disease across the globe, this unique program lays out a simple solution to living to a healthy old age through nutrition. The key is combining the healthy everyday eating plan the book outlines, with the scientifically engineered fasting-mimicking diet, or FMD; the FMD, done just 3-4 times a year, does away with the misery and starvation most of us experience while fasting, allowing you to reap all the beneficial health effects of a restrictive diet, while avoiding negative stressors, like low energy and sleeplessness. Valter Longo, director of the Longevity Institute at USC and the Program on Longevity and Cancer at IFOM in Milan, designed the FMD after making a series of remarkable discoveries in mice, then in humans, indicating that specific diets can activate stem cells and promote regeneration and rejuvenation in multiple organs to significantly reduce risk for diabetes, cancer, Alzheimer’s, and heart disease.

Carl Zimmer presents a history of our understanding of heredity in this sweeping, resonating overview of a force that shaped human society--a force set to shape our future even more radically.She Has Her Mother's Laugh presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

A defining scholarly publication on the past and current state of research with psychedelic plant substances for medicine, therapeutics, and spiritual uses.Certain plants have long been known to contain healing properties and used to treat everything from depression and addiction, to aiding in on one’s own spiritual well-being for hundreds of years. Can Western medicine find new cures for human ailments by tapping into indigenous plant wisdom? And why the particular interest in the plants with psychoactive properties? These two conference volume proceedings provide an abundance of answers.The first international gathering of researchers held on this subject was in 1967, sponsored by the National Institute of Mental Health (NIMH) and U.S. Public Health Service. It was an interdisciplinary group of specialists – from ethnobotanists to neuroscientists – gathered in one place to share their findings on a topic that was gaining widespread The use of psychoactive plants in indigenous societies. The WAR ON DRUGS which intervened slowed advances in this field.Research, however, has continued, and in the fifty years since that first conference, new and significant discoveries have been made. A new generation of researchers, many inspired by the giants present at that first conference, has continued to investigate the outer limits of ethno-psychopharmacology. At the same time, there has been a sea change in public and medical perceptions of psychedelics. There is now a renaissance in research, and some of these agents are actively being investigated for their therapeutic potential. They are no longer as stigmatized as they have been in the past, although they remain controversial. There still remains much work to do in this field, and many significant discoveries remain to be made.So, in June of 2017, once again specialists from around the world in fields of ethnopharmacology, chemistry, botany, and anthropology gathered to discuss their research and findings in a setting that encouraged the free and frank exchange of information and ideas on the last 50 years of research, and assess the current and possible futures for research in ethnopsychopharmacology. The papers given at the 2017 Symposium, organized by Dr. Dennis McKenna, in a handsome two volume boxed collectors set represents perhaps the most significant body of knowledge in this interdisciplinary field available.About Dennis He is an icon amongst psychedelic explorers, working to inspire the next generation of ethnobotanists in the search for new medicines for the benefit of humanity and the preservation of the biosphere that produces what is apparent from reading these papers – a rich pharmacopeia of medicines.Essential for academic libraries, pharmaceutical and ethnobotanical collections.

An eye-opening exploration of blood, the lifegiving substance with the power of taboo, the value of diamonds, and the promise of breakthrough scienceBlood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

An eye-opening report from an award-winning author and former New York Times reporter reveals the link between teenage marijuana use and mental illness, and a hidden epidemic of violence caused by the drug—facts the media have ignored as the United States rushes to legalize cannabis.Recreational marijuana is now legal in nine states. Almost all Americans believe the drug should be legal for medical use. Advocates argue cannabis can help everyone from veterans to cancer sufferers. But legalization has been built on myths– that marijuana arrests fill prisons; that most doctors want to use cannabis as medicine; that it can somehow stem the opiate epidemic; that it is not just harmless but beneficial for mental health. In this meticulously reported book, Alex Berenson, a former New York Times reporter, explodes those • Almost no one is in prison for marijuana;• A tiny fraction of doctors write most authorizations for medical marijuana, mostly for people who have already used;• Marijuana use is linked to opiate and cocaine use. Since 2008, the US and Canada have seen soaring marijuana use and an opiate epidemic. Britain has falling marijuana use and no epidemic;• Most of all, THC—the chemical in marijuana responsible for the drug’s high—can cause psychotic episodes. After decades of studies, scientists no longer seriously debate if marijuana causes psychosis.Psychosis brings violence, and cannabis-linked violence is spreading. In the four states that first legalized, murders have risen 25 percent since legalization, even more than the recent national increase. In Uruguay, which allowed retail sales in July 2017, murders have soared this year.Berenson’s reporting ranges from the London institute that is home to the scientists who helped prove the cannabis-psychosis link to the Colorado prison where a man now serves a thirty-year sentence after eating a THC-laced candy bar and killing his wife. He sticks to the facts, and they are devastating.With the US already gripped by one drug epidemic, this book will make readers reconsider if marijuana use is worth the risk.

OB/GYN, writer for The New York Times, USA Today, and Self, and host of the show Jensplaining, Dr. Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

Getting older doesn’t have to mean experiencing more pain and illness, becoming less mobile, or developing disease. Renowned cardiovascular research scientist and doctor of pharmacy Dr. James DiNicolantonio partners with leading physician and bestselling author Dr. Jason Fung to deliver The Longevity Solution, a groundbreaking new book that unlocks the secrets of healthy aging. Using evidence drawn from their years of medical research and clinical practice, Dr. DiNicolantonio and Dr. Fung lay out five simple, easy-to-follow steps you can take now for a longer, fuller, healthier life.The Longevity Solution explains how to incorporate time-honored wellness traditions while doing away with fads, unnecessary supplements, and unsubstantiated wellness practices. It investigates the dietary habits and other practices of the healthiest, longest-lived humans on the planet, who live in regions known as Blue Zones, as a model for what and how we should eat. It teaches the benefits of intermittent fasting and calorie restriction, which have been shown to slow the aging process, while consuming proper ratios of protein and healthy fats. It also looks at how red wine, tea, and coffee play key roles in optimizing health and why salt is an ally, not an enemy, in the longevity equation.In this comprehensive guide, Dr. DiNicolantonio and Dr. Fung unveil cutting-edge science in an approachable format that is easy to understand and can be put into practice immediately. Simple dietary changes can help you break the cycle of carbohydrate dependence, kick your metabolism into high gear, and jump-start your longevity genes. The Longevity Solution puts healthy aging back in your control!