Stuart A. Kauffman

A major scientific revolution has begun, a new paradigm that rivals Darwin's theory in importance. At its heart is the discovery of the order that lies deep within the most complex of systems, from the origin of life, to the workings of giant corporations, to the rise and fall of great civilizations. And more than anyone else, this revolution is the work of one man, Stuart Kauffman, a MacArthur Fellow and visionary pioneer of the new science of complexity. Now, in At Home in the Universe , Kauffman brilliantly weaves together the excitement of intellectual discovery and a fertile mix of insights to give the general reader a fascinating look at this new science--and at the forces for order that lie at the edge of chaos.We all know of instances of spontaneous order in nature--an oil droplet in water forms a sphere, snowflakes have a six-fold symmetry. What we are only now discovering, Kauffman says, is that the range of spontaneous order is enormously greater than we had supposed. Indeed, self-organization is a great undiscovered principle of nature. But how does this spontaneous order arise? Kauffman contends that complexity itself triggers self-organization, or what he calls "order for free," that if enough different molecules pass a certain threshold of complexity, they begin to self-organize into a new entity--a living cell. Kauffman uses the analogy of a thousand buttons on a rug--join two buttons randomly with thread, then another two, and so on. At first, you have isolated pairs; later, small clusters; but suddenly at around the 500th repetition, a remarkable transformation occurs--much like the phase transition when water abruptly turns to ice--and the buttons link up in one giant network.Likewise, life may have originated when the mix of different molecules in the primordial soup passed a certain level of complexity and self-organized into living entities (if so, then life is not a highly improbable chance event, but almost inevitable). Kauffman uses the basic insight of "order for free" to illuminate a staggering range of phenomena. We see how a single-celled embryo can grow to a highly complex organism with over two hundred different cell types. We learn how the science of complexity extends Darwin's theory of evolution by natural that self-organization, selection, and chance are the engines of the biosphere. And we gain insights into biotechnology, the stunning magic of the new frontier of genetic engineering--generating trillions of novel molecules to find new drugs, vaccines, enzymes, biosensors, and more. Indeed, Kauffman shows that ecosystems, economic systems, and even cultural systems may all evolve according to similar general laws, that tissuesand terra cotta evolve in similar ways. And finally, there is a profoundly spiritual element to Kauffman's thought. If, as he argues, life were bound to arise, not as an incalculably improbable accident, but as an expected fulfillment of the natural order, then we truly are at home in the universe.Kauffman's earlier volume, The Origins of Order , written for specialists, received lavish praise. Stephen Jay Gould called it "a landmark and a classic." And Nobel Laureate Philip Anderson wrote that "there are few people in this world who ever ask the right questions of science, and they are the ones who affect its future most profoundly. Stuart Kauffman is one of these." In At Home in the Universe , this visionary thinker takes you along as he explores new insights into the nature of life.

Consider the woven integrated complexity of a living cell after 3.8 billion years of evolution. Is it more awe-inspiring to suppose that a transcendent God fashioned the cell, or to consider that the living organism was created by the evolving biosphere? As the eminent complexity theorist Stuart Kauffman explains in this ambitious and groundbreaking new book, people who do not believe in God have largely lost their sense of the sacred and the deep human legitimacy of our inherited spirituality. For those who believe in a Creator God, no science will ever disprove that belief. In Reinventing the Sacred, Kauffman argues that the science of complexity provides a way to move beyond reductionist science to something new: a unified culture where we see God in the creativity of the universe, biosphere, and humanity. Kauffman explains that the ceaseless natural creativity of the world can be a profound source of meaning, wonder, and further grounding of our place in the universe. His theory carries with it a new ethic for an emerging civilization and a reinterpretation of the divine. He asserts that we are impelled by the imperative of life itself to live with faith and courage-and the fact that we do so is indeed sublime. Reinventing the Sacred will change the way we all think about the evolution of humanity, the universe, faith, and reason.

How did life start? Is the evolution of life describable by any physics-like laws? Stuart Kauffman's latest book offers an explanation-beyond what the laws of physics can explain-of the progression from a complex chemical environment to molecular reproduction, metabolism and to early protocells, and further evolution to what we recognize as life. Among the estimated one hundred billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.Building on concepts from his work as a complex systems researcher at the Santa Fe Institute, Kauffman focuses in particular on the idea of cells constructing themselves and introduces concepts such as "constraint closure." Living systems are defined by the concept of "organization" which has not been focused on in enough in previous works. Cells are autopoetic systems that build they literally construct their own constraints on the release of energy into a few degrees of freedom that constitutes the very thermodynamic work by which they build their own self creating constraints. Living cells are "machines" that construct and assemble their own working parts. The emergence of such systems-the origin of life problem-was probably a spontaneous phase transition to self-reproduction in complex enough prebiotic systems. The resulting protocells were capable of Darwin's heritable variation, hence open-ended evolution by natural selection. Evolution propagates this burgeoning organization. Evolving living creatures, by existing, create new niches into which yet further new creatures can emerge. If life is abundant in the universe, this self-constructing, propagating, exploding diversity takes us beyond physics to biospheres everywhere.

Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems,contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.

In the tradition of Schrödinger's classic What Is Life?, this book is a tour-de-force investigation of the basis of life itself, with conclusions that radically undermine the scientific approaches on which modern science rests-the approaches of Newton, Boltzman, Bohr, and Einstein. Kauffman's At Home in the Universe, which The New York Times Book Review called "passionately written" and nature named "courageous," introduced pivotal ideas about order and evolution in complex life systems. In investigations, Kauffman builds on these theories and finds that classical science does not take into account that physical systems--such as people in a biosphere--effect their dynamic environments in addition to being affected by them. These systems act on their own behalf as autonomous agents, but what defines them as such? In other words, what is life? By defining and explaining autonomous agents and work in the contexts of thermodynamics and of information theory, Kauffman supplies a novel answer to this age-old question that goes beyond traditional scientific thinking. Much of Investigations unpacks the progressively surprising implications of his definition. Kauffman lays out a foundation for a new concept of organization, and explores the requirements for the emergence of a general biology that will transcend terrestrial biology to seek laws governing biospheres anywhere in the cosmos. Moreover, he presents four candidate laws to explain how autonomous agents co-create their biosphere and the startling idea of a "co-creating" cosmos. A showcase of Kauffman's most fundamental and significant ideas, Investigations presents a new way of thinking about the basics of general biology that will change the way we understand life itself--on this planet and anywhere else in the cosmos.

In the hard sciences, which can often feel out of grasp for many lay readers, there are "great thinkers" who go far beyond the equations, formulas, and research. Minds such as Stephen Hawking philosophize about the functions and nature of the universe, the implications of our existence, and other impossibly fascinating, yet difficult questions. Stuart A. Kauffman is one of those great thinkers. He has dedicated his lifetime to researching "complex systems" at prestigious institutions and now writes his treatise on the most complex system of our universe.A recent Scientific American article claims that "philosophy begins where physics ends, and physics begins where philosophy ends," and perhaps no better quote sums up what Kauffman's latest book offers. Grounded in his rigorous training and research background, Kauffman is inter-disciplinary in every sense of the word, sorting through the major questions and theories in biology, physics, and philosophy. Best known for his philosophy of evolutionary biology, Kauffman coined the term "prestatability" to call into question whether science can ever accurately and precisely predict the future development of biological features in organisms. As evidenced by the title's mention of creativity, the book refreshingly argues that our preoccupation to explain all things with scientific law has deadened our creative natures. In this fascinating read, Kauffman concludes that the development of life on earth is not entirely predictable, because no theory could ever fully account for the limitlessvariations of evolution. Sure to cause a stir, this book will be discussed for years to come and may even set the tone for the next "great thinker."

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