Barry Werth

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research.Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS.You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

In 31 Days , Barry Werth takes readers inside the White House during the tumultuous days following Nixon’s resignation and the swearing-in of America’s “accidental president,” Gerald Ford. The congressional hearings, Nixon’s increasing paranoia, and, finally, the devastating revelations of the White House tapes had torn the country apart. Within the White House and the Republican Party, Nixon’s resignation produced new fissures and battle lines—and new opportunities for political advancement.Ford had to reassure the nation and the world that he would attend to the pressing issues of the day, from resolving the legal questions surrounding Nixon’s role in Watergate, to dealing with the wind down of the Vietnam War, the precarious state of détente with the Soviet Union, and the ongoing attempts to stabilize the Middle East. Within hours of Nixon’s departure from Washington, Ford began the all-important task of forming an inner circle of trusted advisers.In richly detailed scenes, Werth describes the often vicious sparring among two mutually distrustful staffs—Nixon’s and Ford’s vice presidential holdovers—and a transition team that included Donald Rumsfeld (then Nixon’s ambassador to NATO) and Rumsfeld’s former deputy, the thirty-three-year-old coolly efficient Richard Cheney. The first detailed account of the ruthless maneuvering and day-to-day politicking behind everything from the pardon of Nixon to why George H. W. Bush was passed over for the vice presidency, to the rise of a new cadre of Republican movers and shakers, 31 Days offers a compelling perspective on a fascinating but relatively unexamined period in American history and its impact on the present.

In this timely and much praised book, Barry Werth draws upon inside reporting that spans more than two decades. He provides a groundbreaking close-up of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.In 1989, the charismatic Joshua Boger left Merck, then America’s most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company’s tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule , a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex’s bold endurance and eventual success.The $325 billion-a-year pharmaceutical business is America’s toughest and one of its most profitable. It’s riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world’s most regulated industry, matched only by nuclear power.Werth captures the full scope of Vertex’s twenty-five-year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, The Antidote is a powerful inside look at one of the most intriguing and important business stories of recent decades.

Difficulties during the birth of their twins results in one twin's death and the other needing extensive medical care, leading a financially and emotionally troubled family to initiate a lawsuit that consumes seven years of their lives. Reprint.

During his thirty-seven years at Smith College, Newton Arvin published groundbreaking studies of Hawthorne, Whitman, Melville, and Longfellow that stand today as models of scholarship and psychological acuity. He cultivated friendships with the likes of Edmund Wilson and Lillian Hellman and became mentor to Truman Capote. A social radical and closeted homosexual, the circumspect Arvin nevertheless survived McCarthyism. But in September 1960 his apartment was raided, and his cache of beefcake erotica was confiscated, plunging him into confusion and despair and provoking his panicked betrayal of several friends.An utterly absorbing chronicle, The Scarlet Professor deftly captures the essence of a conflicted man and offers a provocative and unsettling look at American moral fanaticism.

The remarkable true story of the longest-held prisoner of war in American history, John Downey, Jr., a CIA officer captured in China during the Korean War and imprisoned for twenty-one years.John (Jack) Downey, Jr., was a new Yale graduate in the post-World War II years who, like other Yale grads, was recruited by the young CIA. He joined the Agency and was sent to Japan in 1952, during the Korean War. In a violation of protocol, he took part in an air drop that failed and was captured over China. His sources on the ground had been compromised, and his identity was known. Although he first tried to deny who he was, he eventually admitted the truth.But government policy forbade ever acknowledging the identity of spies, no matter the consequences. Washington invented a fictitious cover story and stood by it through four Administrations. As a result, Downey was imprisoned during the decades that Red China, as it was called, was considered by the US to be a hostile nation, until 1973, when the US finally recognized the mainland Chinese government. He had spent twenty-one years in captivity.Downey would go on to become a lawyer and an esteemed judge in Connecticut, his home state. Prisoners of Lies is based in part on a prison memoir that Downey wrote several years after his release. Barry Werth fluently weaves excerpts from the memoir with the Cold War events that determined Downey’s fate. Like a le Carré novel, this is a harrowing, chilling story of one man whose life is at the mercy of larger forces outside of his control; in Downey’s case as a pawn of the Cold War, and more specifically the Oval Office and the State Department. His freedom came only when US foreign policy dramatically changed. Above all, Prisoner of Lies is an inspiring story of remarkable fortitude and resilience.

In Banquet at Delmonico’s , Barry Werth, the acclaimed author of The Scarlet Professor , draws readers inside the circle of philosophers, scientists, politicians, businessmen, clergymen, and scholars who brought Charles Darwin’s controversial ideas to America in the crucial years after the Civil War.The United States in the 1870s and ’80s was deep in turmoil–a brash young nation torn by a great depression, mired in scandal and corruption, rocked by crises in government, violently conflicted over science and race, and fired up by spiritual and sexual upheavals. Secularism was rising, most notably in academia. Evolution–and its catchphrase, “survival of the fittest”–animated and guided this Gilded Age.Darwin’s theory of natural selection was extended to society and morals not by Darwin himself but by the English philosopher Herbert Spencer, father of “the Law of Equal Freedom,” which holds that “every man is free to do that which he wills,” provided it doesn’t infringe on the equal freedom of others. As this justification took root as a social, economic, and ethical doctrine, Spencer won numerous influential American disciples and allies, including industrialist Andrew Carnegie, clergyman Henry Ward Beecher, and political reformer Carl Schurz. Churches, campuses, and newspapers convulsed with debate over the proper role of government in regulating Americans’ behavior, this country’s place among nations, and, most explosively, the question of God’s existence.In late 1882, most of the main figures who brought about and popularized these developments gathered at Delmonico’s, New York’s most venerable restaurant, in an exclusive farewell dinner to honor Spencer and to toast the social applications of the theory of evolution. It was a historic celebration from which the repercussions still ripple throughout our society.Banquet at Delmonico’s is social history at its finest, richest, and most appetizing, a brilliant narrative bristling with personal intrigue, tantalizing insights, and greater truths about American life and culture.

HARDCOVER EDITION, 0671723278

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